Body

“CBG works by interacting with the endocannabinoid system (ECS). Together, CB1 and CB2 receptors regulate neurohormones which actively affect physiological processes including mood, metabolism, pain response, and appetite,” (EcoGen LABS)

“Research suggests that CBG can help stimulate the growth of new brain cells – even in elderly patients.” (Hemple)

“It may also stimulate bone growth, relieve pain and reduce inflammation. But that’s not all. It has been shown to have anti-tumor and antibacterial properties, help with glaucoma, mediate bladder dysfunction, manage skin conditions. Like CBD, CBG is also showing benefits for stress, anxiety and depression.” (Hemple)

“CBG may also help with treating glaucoma, because of the way it reduces intraocular pressure. Our eyes contain many endocannabinoid receptors which can be activated by cannabinoids like CBG. When activated, the result can be a shift in intraocular pressure. While cannabinoids, in general, have been suggested as helpful for this, some studies show that CBG may be particularly helpful with decreasing pressure and expediting the draining of fluids.” (Hemple)

“Research also suggests that CBG can be an effective antibacterial agent, particularly against bacterial strains like MRSA, which are resistant to the usual antibiotic drugs. In fact, CBG’s ability to fight against a particular class of bacteria, mycobacteria, and fungi called ‘gram-positive bacteria’ is superior to that of THC, CBD, or CBC. Perhaps in the future, these properties can be harnessed to create a new anti-bacterial treatment.” (Hemple)

“CBG may also be useful for bladder dysfunctions. There are plenty of anecdotal stories of cannabis helping patients with bladder issues. One study looked at the effects of four different cannabinoids (CBG, THCV, CBD and CBDV) on bladder contractions. The researchers found CBG was the most effective at inhibiting muscle contractions in the human bladder. They concluded that it may be useful for treating this uncomfortable symptom of many bladder disorders.” (Hemple)

“Another condition that CBG may be able to help with is psoriasis. In this condition, the normal mechanisms that regulate skin development go awry, leading to thickening and/or reddening of the skin. But CBG inhibits this effect, which researchers suggest could prevent these symptoms. While more human studies are needed, CBG may be a helpful tool in the battle against psoriasis.” (Hemple)

Mood

“A non-intoxicating compound, it’s thought to help regulate mood thanks to its ability to boost anandamide, the body’s native “bliss” molecule, as well as act as a GABA reuptake inhibitor.” (FORBES)

Disease

“CBG is also a potent neuroprotectant and is currently being evaluated for its ability to combat ailments like Huntington’s Disease. It also has cancer-fighting properties and is a potent antibacterial that can even treat MRSA.” (FORBES)

“CBG also shows promise as a cancer-fighter. CBG may help by blocking the receptors that cause cancer cells to grow. In one study on mice with colorectal cancer cells, CBG was able to inhibit the growth of the cancerous cells, slowing down the progression of the disease. In addition, some studies in labs have shown CBG inhibits the growth of prostate cancer cells, while others show inhibition of oral cancer cells. While there is a lot of research still to be done, these studies show exciting possibilities for the treatment of cancer with CBG.” (Hemple)

brain

“CBG is thought to elicit its therapeutic effects directly through interaction with the CB1 and CB2 cannabinoid receptors in the brain.” (Cresco Labs)

“CBG may be most well-known for its potential as a neuroprotectant. This may come from CBG’s anti-inflammatory powers, since inflammation of the brain can play a role in neurodegeneration. In studies of CBG’s effect on mice altered to mimic Huntington’s disease, CBG not only reduced inflammation, it was an active neuroprotectant against degeneration of the brain. In other cases, CBG has even been shown to promote neurogenesis, the growth of new brain cells.” (Hemple)

inflammation

“Another potential use for both CBG and CBGA is as an anti-inflammatory agent. Scientists believe that these compounds may help those with inflammatory conditions, such as inflammatory bowel disease (IBD). One study looked at CBG’s effect on IBD specifically. Scientists induced colitis in mice subjects and looked for inflammatory markers. The researchers found that giving the mice CBG did relieve their inflammation. They suggested human trials following this early indicator of success.” (Hemple)

“We know that CBG shows promise as an antibacterial agent and an anti-inflammatory,” (AXIM Biotechnologies, Inc.)

anxiety

“Finally, researchers have noted that CBG could be helpful for emotional regulation. Studies on rats show that CBG inhibits uptake of the neurotransmitters serotonin and GABA, which can lead to increased serotonin and GABA levels in the brain. This suggests CBG may have antidepressant qualities. And when it comes to GABA, CBG inhibits uptake more effectively than CBD or THC. This is promising news, since CBG is also non-psychoactive, it could be a helpful cannabinoid alternative to THC when it comes to alleviating depression.” (Hemple)